Human parasitaemia levels and its association with Haemoglobin genotype and blood groups among blood donors – M.I.Kooffreh, A.I. Umoyen, and O. Ejarogan
The prevalence of malaria parasitaemia and its possible association with the ABO blood group and haemoglobin genotype among Blood donors in the university of Calabar Teaching Hospital, Calabar was investigated. One hundred and twenty comprising 113 males and 7 females were examined for malaria parasiteamia and test for ABO and genotype using standard procedures. The data was subjected to chi square analysis. The overall prevalence of malaria parasites was 39.17% with a prevalence of 42.86% in females and 38.94% in males though not statistically significant P>0.05. Among age groups, prevalence of malaria parasiteamia was the highest 46.27% in 20-25 years and the lowest 33.33% in 36- 40 years. Plasmodium falciparum was the most prevalent species, accounting for 97.87% of positive cases of malaria parasitaemia, plasmodium ovale accounts for 2.13%. The blood group frequencies were 60.83%, 25.83%, 10.00% and 3.33% in O, A, B and AB individuals respectively, prevalence of malaria parasitaemia varied significantly with blood group B having the highest frequency of 66.67%, 38.36 in group 0, 32.26% in group A and 25% in group AB. Individuals with the AA genotype show a higher prevalence of parasites 45.16% than AS individuals (18.52%). our results reveal that individuals having blood group O (60.83%) and possessing the HBAA genotype are more susceptible to malaria parasitaemia infection.